Flores will exit her role and leave the GAN board of directors with effect from 25 November. She served as CFO for almost three years, having joined the business in January 2020.
Prior to her time with GAN, Flores was vice-president of financial planning and analysis at Alorica, while she also spent time as senior director of financial planning and analysis at The Walt Disney Company.
Flores also worked for Maker Studios, Myspace, Napster, Microsoft and The Clorox Company.
GAN said it had already commenced a search to identify a replacement and has appointed its senior vice-president and corporate controller, Brian Chang, as CFO in the interim.
“Karen’s leadership and financial acumen have been critical parts of GAN’s evolution to a US-listed public company as well as our, at times, complex acquisition of Coolbet in early 2021,” GAN chief executive Dermot Smurfit said. “I am deeply appreciative of Karen’s dedication to GAN and wish her all the best for the future.”
The news comes after GAN earlier this month announced that it was to suspend its revenue guidance for the 2022 financial year due to uncertainties in the market and the Fifa World Cup.
This came despite GAN revealing that Q3 revenue remained relatively flat year-on-year at $32.1m (£26.6m/€30.8m).